The definitive guide to every major psychedelic for scholars.

Ten volumes. Global history, pharmacology and modern practice. Obsessively researched, designed to evolve as the field does.

Mindfield Guides — Ayahuasca: Global History, Pharmacology, and Modern Practice

Ayahuasca

Global History, Pharmacology, and Modern Practice

A definitive single-volume reference on ayahuasca, intended as the first book a serious reader reaches for on the substance. The volume covers origins, pharmacology, the experience, medicine, practice, and the legal and cultural landscape, with the literary quality of long-form journalism and the comprehensiveness of a clinical handbook.

Synthesized from 661 sources, including the peer-reviewed pharmacology, the neuroimaging literature, the global ayahuasca survey, multi-decade ethnography, and the regulatory record.

Coming soon

  • Mindfield Guides — Ibogaine
  • Mindfield Guides — Psilocybin
  • Mindfield Guides — MDMA
  • Mindfield Guides — LSD
  • Mindfield Guides — Mescaline
  • Mindfield Guides — Ketamine
  • Mindfield Guides — Salvia
  • Mindfield Guides — Cannabis
  • Mindfield Guides — DMT

Frequently asked questions

What is Mindfield Guides?

A nine-volume series of reference books, one per major psychedelic substance. Each volume covers global history, pharmacology, the phenomenology of the experience, clinical evidence, practice, harm reduction, legal status, and the open questions the field hasn’t resolved. The goal is to be the first book a serious reader reaches for on a substance, and to stay current as the field moves.

Who wrote this?

AI performed the research, drafted the chapters, and verified every citation against its primary source. A human orchestrated and edited throughout. We’re not hiding the method; it’s central to what Mindfield Guides is. A reference of this scope, updated at the pace the field demands, is what recent advances in AI make possible.

AI makes things up. What makes this different?

The problem with most AI-generated text isn’t the model; it’s the absence of accountability. Every factual claim in Mindfield Guides is anchored to a specific published source. Every citation was run through scite.ai, PubMed, and Semantic Scholar and verified against its primary document before the volume went live. Where a paper couldn’t be independently confirmed, it was cut from the prose. We don’t ask you to trust the AI. We ask you to trust the sources, which are listed and checkable.

Will community members be invited to review each volume?

Yes. Details to be announced.

How often are volumes updated?

Each volume is on a one-to-two year revision cycle, updated whenever significant new research, clinical findings, or legal changes warrant it. Every EPUB carries a version number. Sign up to be notified when a new revision goes live.

When will the next volume be available?

We’re not announcing a schedule. When a volume is ready to the standard the series requires, it goes live. Sign up to be notified.

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